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Steatotic liver disease risk scores compared for predicting cirrhosis

For patients with steatotic liver disease (SLD), the steatosis-associated fibrosis estimator (SAFE) score demonstrated the greatest net bene

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Wellness & Fitness · September 25, 2026
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AI-generated rendition with an imagined camera angle, not a documentary photograph. Source: medicalxpress.com
AI-generated rendition with an imagined camera angle, not a documentary photograph. Source image: medicalxpress.com.

For patients with steatotic liver disease (SLD), the steatosis-associated fibrosis estimator (SAFE) score demonstrated the greatest net benefit for predicting cirrhosis, according to a study published online Sept. 21 in JAMA Internal Medicine.

Catherine Mezzacappa, M.D., Ph.D., M.P.H., from the Yale School of Medicine in New Haven, Connecticut, and colleagues compared the clinical utility of SLD risk scores for predicting cirrhosis and hepatocellular carcinoma (HCC) in patients with noncirrhotic SLD. The cohort study used data from adults with imaging-confirmed SLD in the national U.S.

First reported by Medical Xpress.

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